iPSC Editing & HDR
Efficient HDR and knock-in editing of induced pluripotent stem cells while preserving pluripotency.
Solupore® Integrated RT
Gentle, non-viral transfection — in a compact, easy-to-use device.
The Solupore® Integrated Research Tool (RT) offers reproducible cell engineering for non-viral RNA delivery. Its gentle mechanism maintains viability while delivering efficient payloads for discovery and translational workflows.
Overview
Activation, transfection and early expansion — in one closed consumable.
The RT combines multiple steps into a single closed consumable. Its compact footprint fits small labs, while automated controls minimise hands-on time.
- Reproducible non-viral transfection with minimal cell perturbation.
- Efficient mRNA delivery into primary cells.
- Gentle mechanism preserves cell viability and phenotype.
- Easy-to-use design with a small benchtop footprint.
Applications
Built for discovery and translational research.
mRNA Transfection
Introduce mRNA or RNP complexes into primary cells for transient expression studies.
CD34⁺ / PBMC Reprogramming
Reprogram hematopoietic stem/progenitor cells and PBMCs without affecting viability.
Evidence
Independent studies. Consistent results.
Independent studies show Solupore® Integrated preserves phenotype and viability while delivering high transfection efficiencies. In Kavanagh et al. — Cytotherapy 2021 — non-viral delivery using Solupore® Integrated showed minimal perturbation compared with conventional methods.
Across T cells, NK cells and iPSCs, the RT achieves high editing efficiencies with minimal activation. Customers have used it for CRISPR-mediated knock-ins, prime editing and mRNA transfection with excellent viability and functionality.
For research use only. Not intended for diagnostic or therapeutic use.
Interested in the Research Tool?
Contact us to explore how the Solupore® Integrated RT can accelerate discovery and translational programs.
Enquire About the RT